Muscle spasms

25%

of patients taking TEPEZZA

Patients who had muscle spasms were usually able to manage them. In clinical studies, no patients stopped taking TEPEZZA because of muscle spasms.

Will things such as an ice pack, hot compress, or Epsom salt baths help me with muscle spasms?

Nausea

17%

of patients taking TEPEZZA

Some patients experienced nausea or felt queasy during the first 2 infusions. No one dropped out of the studies due to nausea.

Are there any liquids I should avoid when feeling nauseous? Are there any that I should drink to help with nausea, like water or other clear liquids?

Hair loss

13%

of patients taking TEPEZZA

Some people had hair loss during treatment. All cases of hair loss were mild, with the exception of 1 person who had a moderate case.

Will the hair loss stop after treatment?

Diarrhea

12%

of patients taking TEPEZZA

Almost all cases of diarrhea were mild. Only 1 person had a severe case of diarrhea. That person had a history of ulcerative colitis, which is an inflammatory bowel disease (IBD) that affects the colon.

Would fluids like coffee or alcohol make diarrhea worse? If so, would clear liquids like water or broth be better to drink?

Feeling tired

12%

of patients taking TEPEZZA

Some people felt overly tired and lacking in energy. Most people who reported tiredness had mild cases, while 2 people described their tiredness as moderate.

Would it help to get a good night’s sleep before each infusion, and schedule time afterwards to relax?

High blood sugar

10%

of patients taking TEPEZZA

In some people without diabetes, blood sugar levels became higher than normal. But these levels were managed by their doctors.

In some people who had diabetes, higher blood sugar levels were noticed and treated with changes to their diabetes medicine.

Please see page 14 of this brochure for more information about tracking your blood sugar levels.

Be sure to talk with your doctor about having your blood sugar tested and tracked during treatment.

Here are some questions you may want to ask:

• Who is going to perform the testing?
• Who is going to review the results?
• How often should levels be reviewed?

Hearing problems

10%

of patients taking TEPEZZA

Some people had issues with their hearing, including: deafness, having one or both ears plugged with fluid, a disorder in loudness perception, and an impaired ability to hear certain sounds..

If I’m having issues with hearing, would you recommend seeing an ear, nose, and throat (ENT) doctor?

Taste changes

8%

of patients taking TEPEZZA

Some people described changes to their taste. However, all cases of taste change were mild.

If things start to taste differently, what should I do?

Headache

8%

of patients taking TEPEZZA

All cases of headache were mild.

Would an over-the-counter pain medicine help me with headaches?

Dry skin

8%

of patients taking TEPEZZA

All cases of dry skin were mild.

Would an over-the-counter moisturizing lotion help me with dry skin?

Weight decrease

6%

of patients taking TEPEZZA

Some people taking TEPEZZA lost weight during treatment.

Should I weigh myself regularly during treatment?

Nail Disorder

5%

of patients taking TEPEZZA

Some people saw changes to their nails, including changes in nail color and broken nails. These changes were not painful.

Are there vitamins I can take to keep my nails healthy?